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KMID : 1159320070090030357
Korean Journal of Vision Science
2007 Volume.9 No. 3 p.357 ~ p.376
Corneal erosion and dry eye monitoring using fluorescein stained cornea surface digital photography and other quantitative tests after photorefractive surgery: LASIK vs. LASEK
Kim Yoo-Jin

Doo Ha-Young
Mah Ki-Choong
Abstract
The purpose of this study is to assess the clinical applicability of Oxford corneal stain grading using diagnostic corneal surface digital photography in corneal erosion and dry eye syndrome after corneal refractive surgery.
Two hundred and sixty seven eyes of 134 patients were enrolled in this study. LASIK was performed in 110 eyes and LASEK was performed in 157 eyes. All the surgery was done by a single surgeon. Tear beak-up time(TBUT) and fluorescein stained corneal surface digital photography were performed preoperatively and on postoperative day 7, 1 month, 3 months, and 6 months. Schirmer test was performed preoperatively and on postoperative 1 month and 3 months in order to evaluate the clinical aspects of dry eye syndrome.
Dry eye syndrome which was assessed using TBUT and Schirmer test, was aggravated at early postoperative period but improved after time in both LASIK and LASEK group. Postoperative TBUT and Schirmer test were significantly lower than that of the preoperative in all follow-up periods(p < 0.05) and LASIK group showed significantly lower postoperative TBUT and Schirmer test values than LASEK group(p < 0.05). Fluorescein staining grading showed aggravating corneal erosion until the postoperative 3 months but showed improvement to the preoperative level at postoperative 6 months. Although the LASEK group had more corneal erosion until postoperative day 7, the LASIK group had more corneal erosion on postoperative 1 month and afterwards.
In conclusion, the corneal surface digital photography using fluorescein staining grading is an effective and objective method in assessing the corneal erosion and dry eye syndrome since it can show directly the true morphologic corneal damage and reflect the severity of the disease. Moreover, it showed that LASIK could induce more severe corneal erosion and dry eye syndrome than LASEK.
KEYWORD
Corneal Erosion, Dry Eye Monitoring, Fluorescein Stained Corneal Surface Digital Photography, LASIK, LASEK
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